As mobile app Quality Assurance (QA) engineers, we are constantly on the lookout for the most efficient and effective testing tools to ensure the reliability and functionality of our applications. In this talk, we delve into a comprehensive comparison of three popular mobile testing frameworks: Android Espresso, iOS XCUITest, and Appium. Each tool comes with its unique set of advantages and challenges, and understanding their respective strengths and weaknesses, considering the app design approach is crucial for making informed testing decisions.